Quantification of proteins in ligand binding assays.The use of Chimera’s proprietary multimeric conjugates together with modern substrates opens the door for highly sensitive target quantification.
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The Immunogenicity Gold Standard
MSD-ECL from Meso Scale Discovery is a proven electrochemiluminescence immunoassay platform for large molecule analysis. The ECL technology enables high sensitivity levels combined with broad assay range, making MSD™ ideal for immunogenicity testing, multiplex biomarker screening and cytokine assays.
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20 years of in-depth experience
The award-winning Immuno-PCR (IPCR) based ligand-binding assay platform. Chimera’s proprietary ultra sensitive immunoassay technology that combines the exquisite of ELISA-based antibody specificity with the most sensitive detection system in molecular biology: real-time qPCR.
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Technologies ELISA | Enzyme-linked Immunosorbent Assay Platform for immunoassays
ELISA |
Assay support service
High sensitive ELISA
ELISA (Enzyme linked immunosorbent assays) is the gold standard for the quantification of proteins in ligand binding assays. The use of Chimera’s proprietary multimeric conjugates together with modern substrates opens the door for highly sensitive target quantification.
We offer ELISA immunoassays under GLP, GCP and non-regulated.
Chimera Biotec offers full ELISA testing service for all your bioanalytical needs. Check out our Biomarker Menu for available validated assays. We also develop an highly sensitive ELISA assay based on your specific requirements.
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ELISA | Enzyme linked immunosorbent assay Technology
Sample antigens attached to the plate´s surface are incubated with a target-specific antibody which are linked to an enzyme. Adding the enzyme´s substrate results in a detectable signal, most likely a change in color.
The ELISA platform is available in differented types – Direct ELISA, Sandwich ELISA and Competetive ELISA – each with its own advantages for the experimental set up. Our team of experts will pick the ideal mechanism for your study requirements to ensure optimal sample testing.
Read our case studies and publications to learn more about ELISA.
Efficient ELISA performance by CRO
Precise, fast and reliable realization
Enzyme-linked immunosorbent assays (ELISA) are a widely used method in biomedical research and diagnostics. This technique is based on the specific binding of antibodies to antigens to measure the presence and quantity of certain proteins or molecules in a sample. ELISA is known for its high sensitivity and specificity, making it an indispensable tool in clinical diagnostics and research.
However, performing ELISA requires precise technical skills and extensive experience. An experienced Contract Research Organization (CRO) can ensure that the tests are performed under optimal conditions to achieve accurate and reproducible results. CROs have specialized laboratory facilities and trained personnel who are familiar with the latest technologies and methods, which increases the quality and reliability of the results.
Another benefit of working with an experienced CRO is efficiency and time savings. CROs can process large volumes of samples quickly and efficiently, which is particularly beneficial in time-critical projects. In addition, they can offer customized solutions tailored to the client’s specific needs and requirements, which increases the flexibility and adaptability of the research.
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Locations of the laboratories
Location advantages
Bremen
Our laboratory location in Bremen offers ideal logistical conditions for efficient sample delivery. Thanks to the excellent transport connections, your samples will reach us quickly and reliably. We use our strategically located site to map our fast and smooth logistics processes.
Dortmund
Our laboratory location in Dortmund benefits from the dynamic innovative power of the city, which is known as an important center for technology and research. Together with our laboratory in Bremen, we offer you a high level of redundancy and additional security for your projects thanks to two locations. Take advantage of our first-class infrastructure and secure reliable and continuous support for your biotechnological requirements!
Cost-efficient ELISA tests
Flexibly adaptable for specific study requirements
Enzyme-linked immunosorbent assays (ELISA) are not only precise, but also cost-efficient. This method makes it possible to analyze a large number of samples simultaneously, which significantly reduces the cost per test. By automating many steps, the workload and sources of error can also be minimized, which further increases efficiency.
Another advantage is the flexibility that Chimera Biotec offers. If a study has special requirements, Chimera Biotec can transfer the ELISA assay to another platform. This is particularly useful when specific sensitivities are required that are not available in the original ELISA configuration.
The ability to customize and transfer ELISA assays increases the versatility and applicability of this method. Chimera Biotec can provide customized solutions to meet specific research needs and help achieve the best possible results. This makes ELISA an attractive option for many research projects.
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CENiBRA: Chimera Biotec’s Sales Partner
CENiBRA life science solutions is chimera biotecs sales and distribution partner.
Chimera’s ELISA expertise
The ELISA (enzyme-linked immunosorbent assay) method offers an excellent combination of sensitivity and specificity, which is essential for many research applications. When a CRO like Chimera Biotec GmbH performs these assays, customers benefit from an excellent price-performance ratio. Chimera Biotec GmbH uses state-of-the-art technologies and optimized processes to deliver precise and reliable results. Through the efficient use of resources and the expertise of the team, costs can be reduced while maintaining high quality standards. This makes Chimera Biotec GmbH a cost-effective choice for your ELISA requirements without compromising on accuracy and reliability.
Platform intrinsic advantages
- Highly sensitive assays
- Fast and automated platform
- Wide range of assay kits
Our services at a glance
- In-house antibody pair testing
- Assay development services
- Multiplex biomarker assays
- PK assays
- Assay transfer
- Assay validation (fit-for-purpose, non-reg., GLP confirm validation)
- Regulated bioanalysis (non-reg / GCP / GLP)
Take advantage of Chimera Biotec‘s more than 20 years of in-depth experience as a specialty CRO for immunoassays which go beyond the scope of what is usually considered feasible.
Benefit from the best in class in immunoassay sensitivity!
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Discover the benefits of our first-class solutions! Press the contact button now to arrange a free meeting with one of our scientists. Take advantage of this unique opportunity to clarify your questions and receive individual advice for your projects. Let our expertise convince you and take your research to the next level!
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High sensitivity ELISA (HS ELISA) immunoassay services:
Our expertise in detection conjugate synthesis and state of the art signal amplification chemistry allows us to optimize ELISA performance. Starting from commercially available kits and reagents, we provide cost effective biomarker quantification to fulfill your requirements within ELISA technical limitations. Custom PK assay development based on your drug specific reagents or uncommon biomarkers is available up to GLP/GCP conform validation and bioanalysis.
Benefit from the best in class in immunoassay sensitivity!
Technologies Imperacer Assay testing services
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