Precision Bioanalysis Powered by ABclonal
Strategic Partnership
Advanced antibodies meet ultra-sensitive assays for breakthrough drug development precision.
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ABclonal & Chimera Biotec – Precision in Immunoassays
Strategic Partnership with ABclonal: Elevating Assay Performance with Next-Generation Antibody Solutions
To further enhance the sensitivity, specificity, and reproducibility of our regulated bioanalytical services, Chimera Biotec has entered a strategic partnership with ABclonal, a global leader in antibody innovation.
ABclonal is renowned for its cutting-edge recombinant rabbit monoclonal antibodies, which offer superior performance in terms of specificity, sensitivity, and batch-to-batch consistency. These next-generation antibodies are now being integrated into Chimera’s validated assay platforms — including Immuno-PCR (Imperacer®), Simoa®, MSD®, and ELISA — to deliver even more robust and reliable ligand binding assays.
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By combining ABclonal’s deep expertise in antibody design and engineering with Chimera’s proven capabilities in ultra-sensitive immunoassay development, this collaboration enables:
- Enhanced assay sensitivity and specificity for pharmacokinetics, biomarker discovery, and immunogenicity testing
- Improved reproducibility across all phases of drug development
- Faster timelines through optimized antibody performance
- Full regulatory compliance in GLP/GCLP environments
This partnership reflects our shared commitment to scientific excellence and innovation — helping our clients accelerate the development of safer, more effective therapeutics.
Discover the power of precision bioanalysis — now strengthened by ABclonal’s antibody technology.
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Benefit from more than 20 years of experience in PK assay development
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Sensitivity meets assay range: One of Chimera’s major expertise is ultra-sensitive PK study support. Combining a broad quantitative range with an excellent sensitivity, we offer unmatched biologics PK support using a single assay format. From high dosing in TOX studies through extremly low dosing in dose escalation in the later clinical stage- Chimera provides regulated PK sample testing using validated methods, based on the same assay format adapted to the intended range of application. This eliminates the need to run several assays to pair sensitivity and dynamic assay range.
- PK profile: Chimera’s capability to measure low concentrations of a given drug, we are able to provide a complete PK profile even for initial doses and thus shorten Phase I trials. Our high-quality data meets your regulatory requirements and can be decisive to evaluate drug distribution and clearance behaviors.
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PK PA assay testing in rare matrices
Chimera’s long-running experience in diverse and rare matrices helps to understand the pharmacokinetic profile of your drug compound in virtually any matrix:
- Serum/ plasma
- Cerebrospinal fluid (CSF)
- Cell culture medium
- Bronchoalveolar lavage fluid (BALF)
- Tissue extracts and lysates
- Mouse tail vein
- Tears
- Saliva
- Synovial fluid
- And many more
PK PD assay testing service – Step by step –
1. Click on the button below and tell our science team what your challenge is.
2. We will arrange a meeting with you under CDA conditions.
3. You will receive an offer from us that meets all your requirements.
We look forward to your challenge.
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Selection of PK studies supported by Chimera:
- Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.
Access here
- Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033
Access here
- Phase I trial of intravenous aviscumine (rViscumin) in patients with solid tumors: a study of the European Organization for Research and Treatment of Cancer New Drug Development Group
Access here
Unmatched sensitivity in PK PD Assay Service
PK PD assay services: Case studies
LBA bioanalytical PK support for biologics: The need for sensitivity combined with a broad assay range:
Request the poster including three case studies, that show ultra-sensitive therapeutic antibody quantification in biological matrix.
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Questions about our PK PD Assay Services ?
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Discover the benefits of our first-class solutions! Press the contact button now to arrange a free meeting with one of our scientists. Take advantage of this unique opportunity to clarify your questions and receive individual advice for your projects. Let our expertise convince you and take your research to the next level!
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Find out how Chimera Biotec can advance your research!
Empowering your scientific discoveries.
